Mederma: The safety and efficacy


Scarring is often a cosmetic problem after minor and major surgeries. The skin of some people has the tendency to form large scars, ugly forms, even after minor skin lesions.

Therefore, many products have been developed for wound healing and scar healing, and thus to prevent these complications. Mederma is a product for skin care developed by the pharmaceutical Merz. It is intended for the treatment of scars, and the manufacturer claims it helps reduce scarring and improve the healing process of the skin.


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Scarring is a natural healing process in response to tissue damage. Almost all human tissues have a tendency to form scars, with the exception of some self-regenerative, tissues such as liver and bones.

Scar intensity depends on the severity of the wound. If the wound is superficial, and if its edges are close, scarring will be minimal because the skin cells are able to proliferate and reduce the gap. However, if a wound is wide and deep, especially if a certain amount of tissue is not present, the skin cells are unable to bridge the gap and a large amount of scar tissue is formed to replace normal tissue. Scar tissue is composed of collagen fibers, and its protective properties are approximately 80% of normal skin. Scars have no skin appendages such as hair follicles, sweat glands and sebaceous, and are more susceptible to damage caused by mechanical factors and light.

The active ingredient in Mederma is the extract of the common onion. The onion extract has been traditionally used to treat many diseases of the skin; it has been shown useful in some cases.


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Onion is a source of various biologically active, such as thiosulfates, bioflavonoids, and metalloproteinases substances.In some studies it has been shown to promote wound healing and reduce scarring. Mederma manufacturers claim that the appearance of new surgical scars can be significantly improved after application 3 times a day for 2 or 3 months.The results of scientific studies were generally satisfactory, but the only randomized controlled study was conducted in cooperation with Merz, so there is a risk of bias.

Side effects and safety of Mederma

Mederma is generally well tolerated. In one study, 6 of 44 individuals were itching, burning or reddening of the skin due to dermatitis contact. All unwanted effects disappear spontaneously after stopping treatment. There were no lasting consequences of treatment Mederma.

Allergic to onions or other components of Mederma people cannot use this product. If you suffer from a chronic skin condition, consult your doctor before using Mederma.

Written by Administrator

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